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Magnetic particles offer cancer diagnosis and treatment

Diagnostics - A multi-disciplinary team of scientists are paving the way for the development of a powerful new strategy for both the early diagnosis and treatment of prostate cancer.

The University of Leicester researchers say that microscopic (5-100nm) magnetic nanoparticles could be applied in the sensitive diagnosis and effective treatment of prostate cancer. This follows breakthrough nanotechnology research at the University.

Dr Wu Su of the Department of Chemistry said this technology requires a multidisciplinary approach: "Prostate cancer cure rates are predicated on early diagnosis and treatment. The technology that we are developing offers the potential of both the identification and treatment of prostate cancer in a highly selective manner."

High-performance magnetic nanoparticles act as probes that show up (using magnetic resonance imaging) and kill (by hyperthermia) tumour cells at a much earlier stage than conventional methods.

The technology is focused on the development of a new type of magnetic nanoparticle in which the magnetic performance is increase by a factor of ten. Targeting these magnetic nanoparticles to unique cell surface receptors present on the prostate tumour cell surface will enable efficient and specific delivery to the diseased area. The approach is general and it is envisaged that these systems could be applied to other types of aggressive cancers in which early diagnosis and treatment is essential for recovery.

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